WebOct 3, 2024 · The positive correlation of CXCR3B expression with cancer stem cell properties is not unique to MDA-MB-231 cells. In the luminal breast cancer cell line … WebIncreased ALDH1 expression has been reported in some lung cancer cell lines, malignant transformation of lung cells, 12,13 and lung tissues. 14 However, which ALDH1’s …

ALDH1: A potential therapeutic target for cancer stem cells in solid tum…

WebDue to the detection of cancer stem cells via the expression of biomarkers, tumour initiating cells have been identified in leukemia (CD34 +, CD38 −) and in solid tumours including … WebJun 13, 2015 · ALDH1 protein expression was determined in benign breast disease and breast cancer tissues. Of 21 benign breast disease tissues, ALDH1 was only expressed in epithelial cells in 3 cases; while ALDH1 was expressed in tumor cells in 61.0 % (100/164, three cases not available) of 164 breast cancer cases (Fig. 1 ). friends of stower seven lakes state trail

Unraveling the roles of CD44/CD24 and ALDH1 as cancer stem

WebOct 8, 2013 · Cancer stem cells (CSC) or cancer stem cell-like cells (CSC-LCs) have been identified in many malignant tumors. CSCs are proposed to be related with drug resistance, tumor recurrence, and metastasis and are considered as a new target for cancer treatment; however, there are only a few reports on CSCs or CSC-LCs in renal cell … WebJul 7, 2015 · Aldehyde dehydrogenase 1 (ALDH1) is widely used as a specific cancer stem cell marker in a variety of cancers, and may become a promising target for cancer therapy. However, the role of its expression in tumor cells and the microenvironment in different cancers is still controversial. Methods WebALDH as a Marker of Cancer Stem-Like Cells Over the past decade, investigation of ALDH expression by stem cells has been focused on so-called cancer stem-like cells (CSCs) [ 55, 56 ]. First described in leukemia [ 57 ], CSCs were subsequently identified in breast cancer [ 58] and other solid tumors. fbca weekday childhood ministry