Clearing lipemic specimens
WebPrecision, linearity with dilution, lipemic interference, and three methods for removing lipemia were assessed on each platform: ultracentrifugation (UC), lipemia-clearing reagent LipoClear (LC), and 1:5 dilution (DIL). Lipemia-index (L-index) thresholds were established using endogenously lipemic specimens and sera spiked with human-derived ... WebSep 1, 2024 · Lipemic specimens contain high levels of triglycerides consisting of chylomicrons and very low-density lipoprotein particles, which in turn cause …
Clearing lipemic specimens
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WebMay 1, 2024 · UC was effective at clearing lipemic interference, although persistence of residual VLDL was often observed. This study provides an analysis of L-index thresholds for seven immunoturbidimetric assays. Due to the variety of human lipoproteins, limits defined using endogenously lipemic patient specimens may be different from those derived … WebNov 15, 2013 · UC was effective at clearing lipemic interference, although persistence of residual VLDL was often observed. This study provides an analysis of L-index thresholds for seven immunoturbidimetric assays. Due to the variety of human lipoproteins, limits defined using endogenously lipemic patient specimens may be different from those derived …
WebFeb 22, 2016 · A: Lipemia in a blood specimen used for clinical evaluation can cause significant interference with obtaining accurate test values. Lipemia creates turbidity of a sample and is a result of the accumulation … WebIt is likely to cause artifactually high estimates of the plasma protein level as determined by refractometry. Lipemia may have adverse effects on many serum/plasma biochemical tests. Specific effects depend upon the methodology used, the severity of the lipemia, and the laboratory's success in clearing lipemia prior to specimen analysis.
WebAvoid lipemia: cloudy or milky serum sometimes due to the patient's diet (discussed under the section on lipemia). Plasma Preparation. The most common considerations in the preparation of plasma: Collect specimen in additive indicated in the test requirements. Mix specimen with additive immediately after collection by inverting 5-10 times. WebJun 22, 2016 · Reporting of results should include notation of lipemia and how the specimen processing was modified. Zeng et al. employed a correction formula that appears to be fairly reliable. 3 The lipemic whole …
WebUnlike for other interferences, lipemia can be removed and measurement can be done in a clear sample. However, a protocol for removing lipids from the sample has to be chosen …
WebThe Lipemic Serum Clarification System The Lipemic Serum Clarifi cation System clears blood samples of lipemia caused by chylomicrons—fat particles 80–500 nm in diameter that impair accuracy of … potbelly eagan mnWebMar 1, 2014 · UC was effective at clearing lipemic interference, although persistence of residual VLDL was often observed. This study provides an analysis of L-index thresholds for seven immunoturbidimetric assays. Due to the variety of human lipoproteins, limits defined using endogenously lipemic patient specimens may be different from those derived … toto barWebNov 1, 2024 · Lipemic specimens are a common and frequent, but yet unresolved problem in clinical chemistry, and may produce … potbelly east legonWeb[3]. Several studies have shown that an altered or reduced ability to clear TG in the postprandial period (thus, a large postmeal TG response) is associated with CVD [3,10,11,12]. What is lipemic or Lactescent specimen? Lipemia (lactescence) is caused by increased triglycerides (usually as chylomicrons and infrequently from high … potbelly east lansingtoto bathroom faucets partsWebNov 15, 2024 · Lipid-clearing agents were uniformly effective for seven analytes: ALT, AST, total bilirubin, CK, creatinine (Jaffe method), lipase, and urea. Mixed results were … potbelly east beltlineWebFeb 9, 2024 · Among the different treatments for clearing lipemia, previous reports have described the effectiveness and benefits of using UC. 16, 17, 25 In the present study, although not statistically significant, several analytes showed trends toward percentage differences greater than our acceptability criteria with UC: pancreatic CA 19-9 (–29% ... toto band tour 2020