WebHigh-LD Regions explains how to identify predictors in high-LD regions when analysing human data. If there are no predictors in high-LD regions, you should use --check-high … WebThe high LD found among the 12 SNPs indicated that those unknown chromosomal positions were part of the translocation that was not well mapped to the reference …
Detection and quantification of inbreeding depression for complex ...
Web14 de set. de 2004 · Moreover, in high LD regions, the proportion of variation explained by htSNPs in UK Caucasian sample was nearly unchanged when those same SNPs were applied to CEPH data (all differences in haplotype r 2 ≤0.07). A main outcome from the present study concerns the relationship between marker density and tag SNP selection. Web26 de jul. de 2024 · However, if the causal variants are enriched in high-LD regions of the genome, b UNI will overestimate the actual inbreeding depression. In contrast, if the causal variants are enriched in a low-LD region like DNAse-I hypersensitive sites or enhancers ( 18 ), or if they are enriched among low-frequency variants, b UNI is expected to … briggs and riley
Regions of high linkage disequilibrium (LD) - Genome Analysis Wiki
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