Lamp1是什么的标记物
Tīmeklis2024. gada 23. janv. · 分子伴侣蛋白识别带有特定氨基酸序列的底物蛋白质分子, 并与之结合, 然后再经溶酶体膜上的受体 Lamp2a(lysosome-associated membrane protein 2, Lamp2) 转运到溶酶体;底物蛋白分子再在溶酶体内, 被水解酶降解。 因此, 分子伴侣介导的自噬与前两者不同, 在降解蛋白时具有选择性。 而大自噬和小自噬现象 … TīmeklisULK 是自噬信号通路唯一一个具有丝氨酸/苏氨酸激酶活性的核心蛋白。 在自噬溶酶体组装前自噬信号是通过由 ULK1 或 ULK2、FIP200 和 mATG13 组成的 ULK 复合物的活化介导的。 ULK1 复合物在体内是连接上游营养或能量感受器 mTOR 和 AMPK 与下游自噬体形成的桥梁。 磷酸化的 ULK1 一直以来都被认为是自噬的一个关键调控因子,目 …
Lamp1是什么的标记物
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TīmeklisLAMP1. LAMP1 and LAMP2 are major protein components of the lysosomal membrane and play important roles in lysosome biogenesis and autophagy, whereas Rab7 is … TīmeklisLAMP1 抗体 (H4A3) 推荐用于 WB, IP, IF, IHC (P) 和 FCM,检测mouse, rat 和human 来源的 LAMP-1; 也和以下物种反应,包括: monkey 抗-LAMP1 抗体 (H4A3) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC (P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 …
TīmeklisLysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal membrane proteins in five mammalian cultured cell lines. Rat LAMP1 fused to enhanced green fluorescent protein (EGFP) mostly accumulate … Tīmeklis2024. gada 8. sept. · 艾美捷 Atlas Antibodies 一系列的细胞器标志物抗体(如GJB6抗体、LAMP1抗体、CDK5RAP2抗体、CEP350抗体、DES抗体等),能在蛋白水平进 …
Tīmeklis概述 产品名称 Anti-LAMP1抗体- Lysosome Marker 参阅全部 LAMP1 一抗 描述 兔多克隆抗体to LAMP1 - Lysosome Marker 宿主 Rabbit 经测试应用 适用于: IHC-P, WB more details 种属反应性 与反应: Human 预测可用于: Mouse, Rat, Chicken, Hamster, Cow, Cat, Dog, Xenopus laevis, Monkey, Zebrafish, African green monkey 免疫原 TīmeklisLAMP1(溶酶体相关膜蛋白1)和LAMP2分布在自噬和溶酶体细胞器中。 尽管分布广泛,但LAMP1通常用作溶酶体标记物,而LAMP1阳性细胞器通常称为溶酶体区室。 通过应用免疫电子显微镜(iTEM)和共聚焦成像与Airyscan显微镜相结合,我们扩展了有限的文献,以提供LAMP1在神经元中各种自噬和溶酶体细胞器中分布的全面和定量分析。 …
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic cancers such as pancreatic cancer Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … Skatīt vairāk
http://www.bjbalb.com/html/Recombinant-Protein/JN1133.html champions league redrawnTīmeklis2024. gada 10. sept. · 溶酶体相关膜蛋白1(LAMP1)也称为CD107a(分化簇107a)。. LAMP1/CD107a属于灯系列。. 这种糖蛋白为选择素提供碳水化合物配体。. 它也可 … champions league rb leipzig im tvTīmeklisLAMP1 signals were readily detected around the surface of various endosome- and lysosome-like organelles including mature lysosomes with a high electron density, … hapus background imageTīmeklis溶酶体相关膜蛋白LAMP1 (lysosome-associated membrane protein 1)是主要存在于溶酶体膜上的一种高度糖基化的糖蛋白,参与细胞内多种生理和病理过程.近年有关LAMP1 … champions league redrawTīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite … hapus background jpgTīmeklis2024. gada 28. jūl. · LAMP1/2 是溶酶体相关膜蛋白,相关抗体可用于标记溶酶体。 自噬信号通路的研究 自噬在细胞存活与死亡中是把双刃剑,既能促进细胞存活也会导致细胞凋亡,但其具体机制还有待研究,阐明自噬在细胞存活和死亡方面的作用机制,深入了解自噬信号通路有助于我们更好的理解自噬在维持细胞内稳态的作用,并了解其在肿瘤、 … champions league referee salaryTīmeklis溶酶体相关膜蛋白 1: 由该基因编码的蛋白质是膜糖蛋白家族的成员。这种糖蛋白提供带有碳水化合物配体的选择素。它还可能在肿瘤细胞转移中发挥作用。[RefSeq 提 … champions league record top scorer