WebThermo Scientific TheraPure®phosphoramidites are designed for oligonucleotide manufacturers requiring highly defined impurity profiles and strictly controlled processes. A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety. See more Nucleoside phosphoramidites Phosphoramidites derived from protected nucleosides are referred to as nucleoside phosphoramidites and are widely used in chemical synthesis of DNA, RNA, and other nucleic acids … See more • Phosphoramidate See more
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WebThe phosphoramidite DNA synthesis cycle consists of a series of steps outlined in Figure 1. Figure 1 The phosphoramidite oligonucleotide synthesis cycle phosphoramidite-oligonucleotide-synthesis-cycle: Typical timings used for the synthesis of DNA oligonucleotides in the phosphoramidite cycle Detritylation of the support-bound 3' … WebPhosphoramidite. Nucleoside phosphoramidites are used to synthesise short nucleic acid chains. The chemical process allows several modifications, such as linker arms or using alternative nucleotides, such as LNA or morpholino or 2' group modified (OMe, NH 2, F) or abasic, non-canon bases (xanthine, hypoxanthine, tricyclic bases, etc) or bases ... rawson accommodation victoria
Nucleoside phosphoramidite - Wikipedia
WebAbout Us. As a trailblazer in DNA and RNA manufacturing, ChemGenes is redefining the limits of scientific discovery and innovation. We are the market leader in nucleic acid … WebPhosphoramidite chemistry, developed in the 1980s and later enhanced with solid-phase supports and automation, is the method of choice for DNA oligonucleotide … WebPhosphoramidites Phosphite diester monoamides with high reactivity towards nucleophiles that can be catalyzed by weak acids. Nucleoside phosphoramidites can be derived from natural or synthetic nucleosides, and are used to synthesize oligonucleotides. Filter By category Nucleic Acid Synthesis Phosphoramidites (2) Glen Research (1) simple light fixtures ceiling