Protein ndrg1 isoform 2
WebbThe protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, ... such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, ... WebbN-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion. Lane DJ et al. PLoS One 2013;8 …
Protein ndrg1 isoform 2
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WebbThe Tissue section contains information regarding the expression profile of human gene both on the mRNA and protein level. The protein expression data from 44 normal tissue … Webb15 maj 2013 · The NDRG1 gene has been mapped to chromosome 8q24.3 (8q24.2 in other studies) ( 5), which is approximately 60kb in length ( 1, 5, 6). This gene encodes a 3.0kb messenger RNA (mRNA) that itself encodes a very stable, 43kDa NDRG1 protein (composed of 394 amino acids), which is highly conserved among multicellular …
WebbNX_Q92597 - NDRG1 - Protein NDRG1 - Proteomics. Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many … Webb9 apr. 2024 · Organism Homo sapiens Position chr8:133239035 (GRCh38.p13) Help. The anchor position for this RefSNP. Includes all nucleotides potentially affected by this …
WebbNDRG1 - Function 1 GENE 3 ISO 282 REF Gold Only Extend overview NDRG1 → Protein NDRG1 Protein also known as : Reducing agents and tunicamycin-responsive protein (RTP) . Gene name : NDRG1 Family name : NDRG Entry whose protein (s) existence is based on evidence at protein level. Show evidences
Webb22 nov. 2024 · NDRG1). (B) Isoform 2 with 66 amino acid ... cumulation of pro-apoptotic protein BAX and a decrease in anti-apoptotic proteins Bcl-2 . and Bclxl, indicating NDRG1-mediated inhibition of apoptosis.
As reviewed by Kovacevic et al., NDRG1 is a potent, iron-regulated growth and metastasis suppressor that was found to be negatively correlated with cancer progression in a number of tumors, including prostate, pancreatic, breast, and colon cancers. NDRG1 has marked anti-oncogenic activity, being associated with decreased cell proliferation, migration, invasion, and angiogenesis. The molecular functions of NDRG1 affect numerous signaling pathways that regul… bri doakWebbNDRG1 iso2 Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not … taste paradise menuWebbMetrics, metrics, metrics: Measuring the Impact of UniProt. UniProt is brought to you by a large team of dedicated scientists who have worked for over 20 years to produce a comprehensive view of protein sequence and biology. protein spotlight. tastergehäuse edelstahlWebb26 mars 2024 · N-myc downstream regulated gene 1 (NDRG1) is an intracellular protein involved in cell differentiation and was recently reported to exert various effects in several cancers. However, its ... taste paradise jakartaWebb10 dec. 2024 · Crystal structures of the α/β hydrolase domain of human NDRG2 isoform 2 ... in the presence of Co 2+ NDRG1 lost 10% of its α-helical content (Fig. 5D). ... taste ramadan liverpoolWebbFT CHAIN 2-394 Protein NDRG1. Molecular weight (Da) 42704.25 Theoretical pI . 5.49 NDRG1 Protein Interaction . Recombinant NDRG1 Protein Feature . NDRG1 Protein, … taste pptWebbNDRG1 Imported Organism names Organism Homo sapiens (Human) Imported Taxonomic identifier 9606 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > … brid nogol